معرفی
Sabrina Diano is an Adjunct Professor in the Department of Cellular & Molecular Physiology at Yale University School of Medicine, with affiliations in Neurobiology and Comparative Medicine. She is part of the Integrative Cell Signaling and Neurobiology of Metabolism (ICSNM) and the Interdepartmental Neuroscience Program. Dr. Diano holds a PhD from the University of Naples and joined Yale’s faculty in 2000 after postdoctoral training there.
Her research focuses on hypothalamic mechanisms regulating energy and glucose homeostasis, with implications for metabolic syndrome, obesity, and type 2 diabetes. Key areas include POMC neuron function, mitochondrial dynamics, and leptin/glucose sensing pathways. Recent work explores ceramide metabolism in endothelial cells and microglial roles in metabolic control.
Awards include the Helmholtz Diabetes Award (2018) and an endowed professorship. She collaborates frequently with Tamas Horvath and Zhongwu Liu, among others. Her lab (Diano Lab) investigates central nervous system interactions with metabolic processes, leveraging interdisciplinary approaches in physiology, molecular biology, and neuroendocrinology.
Publications span topics like cannabinoid-induced feeding, mitochondrial uncoupling protein 2 (UCP2), and prolylcarboxypeptidase (PRCP) regulation of melanocortin signaling. Her work bridges basic science and clinical relevance, addressing metabolic disorders’ pathogenesis and potential therapies.
