Russell Ryan

Russell Ryan is an Assistant Professor in the Department of Pathology at the University of Michigan Medical School. His research focuses on transcriptional regulation in hematologic malignancies, particularly leukemia and lymphoma.

• Collaborates with Mark Chiang's lab and NYU Grossman School of Medicine
• Expertise in enhancer hijacking, MYC activation, and stem cell transcriptional networks
• Develops genomic tools like Hi-C for detecting oncogenic rearrangements

Recent work explores:

• Stem cell transcriptional circuits in T-cell leukemia
• Enhancer dependencies in MYC-driven lymphomas
• EZH2-mediated immune evasion in pediatric AML
• Notch signaling in T-ALL stress response

Publications across Blood, JEM, and Cancer Research demonstrate his interdisciplinary approach combining mouse/human models with advanced genomic technologies.