معرفی
Ruben Dagda is an Associate Professor in the Department of Pharmacology at the University of Nevada School of Medicine, where he investigates molecular mechanisms of mitochondrial dysfunction and oxidative stress in Parkinson's disease using cell, tissue, and animal models. He has authored 68 publications and mentored over 30 undergraduate students, 5 graduate students, and 3 postdoctoral scholars.
- Education:
- B.S., Biology, University of Texas at El Paso
- M.S., Biology, University of Texas at El Paso
- Ph.D., Pharmacology, University of Iowa School of Medicine
His research focuses on prosurvival signaling pathways regulating mitochondrial function, transport, and turnover in neurons, with a specific emphasis on aging and neurodegenerative diseases like Parkinson's. He aims to develop small molecular drugs to reverse neurodegeneration and enhance mitochondrial function in age-related conditions.
The recent publications highlight mitochondrial biology, neurodegenerative disease modeling, and pharmacological interventions, including BDNF-TrkB signaling in neurons, toxin-induced mitochondrial damage, and therapeutic strategies using nootropics with nanoparticle delivery systems.
Ruben Dagda's laboratory has trained numerous students and postdoctoral scholars in mitochondrial pharmacology and neurodegenerative disease research, emphasizing hands-on experience with advanced techniques like Seahorse XFe24 bioenergetics analysis and ImageXpress Nano imaging platforms.
