Ross Bathgate

Professor Ross Bathgate is a leading academic at The Florey Institute and an Honorary Professorial Fellow in the Department of Biochemistry and Molecular Biology at the University of Melbourne. His research focuses on neuropeptide interactions with G protein-coupled receptors (GPCRs) for therapeutic drug design, particularly in the relaxin family of peptides.

• Key Projects: Developing relaxin analogs (B7-33, H3) for antifibrotic and pain treatments, INSL5 analogs for colon motility, and novel GPCR-targeting drugs.
• Research Impact: Over 250 publications, including Phase III clinical trials for relaxin in acute heart failure.

Collaborations: Works with pharmaceutical companies on clinical development of relaxin and other peptide GPCR therapeutics.

Notable Article Trends: Focus on structure-based drug design, GPCR dynamics, and translational applications for cardiovascular and gastrointestinal diseases.

Labs & Teams: Leads the Neuropeptide Receptor Group at Parkville Campus, University of Melbourne, specializing in peptide-GPCR interactions.