معرفی
Robert Wiseman is a Professor at Michigan State University with primary affiliation in the Department of Physiology. His additional academic roles include faculty membership in the Genetics & Genome Sciences Program and professorship in the BioMolecular Science Gateway.
- Department of Physiology
- Genetics & Genome Sciences Program
- BioMolecular Science Gateway
His research centers on metabolic regulation in excitable tissues (skeletal muscle, brain, and heart), with emphasis on skeletal muscle as the body's largest organ system (40-45% of body mass) critical for glucose homeostasis. Key interests include functional imaging of cellular processes, stress adaptation mechanisms, stem cell plasticity, blood flow dynamics, and mitochondrial function in metabolic disorders.
Analysis of his 2018-2019 publications reveals consistent focus on microvascular dysfunction in metabolic syndrome and diabetes, skeletal muscle bioenergetics, and causal relationships between obesity/inactivity versus hyperglycemia in exercise intolerance. His work predominantly employs rodent models and integrates physiological measurements with advanced imaging techniques.
Dr. Wiseman leads a laboratory utilizing multimodal approaches including:
- Magnetic resonance imaging/spectroscopy for non-invasive blood flow and energy dynamics measurement
- Mathematical modeling and computational analysis
- High-resolution respirometry
- Genetic modifications in transgenic animals
- Viral vector-mediated metabolic challenge induction
