معرفی
Richard Huganir is a Bloomberg Distinguished Professor at Johns Hopkins University, holding dual appointments in the School of Medicine (Department of Neuroscience) and the Krieger School of Arts & Sciences (Department of Psychological & Brain Sciences). He is also Director of the Solomon H. Snyder Department of Neuroscience and Co-Director of the Johns Hopkins Brain Science Institute. His research focuses on molecular and cellular mechanisms regulating neurotransmitter receptors and synaptic plasticity, particularly glutamate receptors' roles in learning, memory, and neurological disorders. Huganir has pioneered studies on receptor phosphorylation, synaptic targeting, and trans-synaptic signaling molecules like neuronal pentraxins. His work has revealed critical roles for proteins such as GRIP, PICK1, and synGAP in synaptic function and disease. Recognized with major awards including membership in the National Academy of Sciences and leadership roles in neuroscience organizations, Huganir's contributions bridge basic neuroscience and clinical insights into conditions like schizophrenia, autism, and Alzheimer's disease.
- Education: PhD in Biochemistry, Molecular & Cell Biology from Cornell University (1982)
- Postdoctoral Training: Yale University School of Medicine with Paul Greengard
Research interests include synaptic receptor dynamics, neural circuit plasticity, and translational applications of synaptic biology. His lab employs molecular, biochemical, and imaging techniques, collaborating on projects like CARP (Calcium-permeable AMPA Receptor Plasticity) and bioengineered synapse models. Current efforts explore how synaptic dysfunction underlies neuropsychiatric disorders and develop molecular tools to visualize synapse function in vivo.
