Renny Franceschi

Renny Franceschi, Ph.D., is a Professor in the Department of Biomedical Engineering at the University of Michigan's School of Dentistry. His research focuses on biomechanics, biomedical ultrasonics, and regenerative medicine, with a particular emphasis on collagen receptors like DDR2 and their roles in bone development, regeneration, and tissue engineering. He leads studies on osteogenesis, stem cell behavior, and the application of advanced materials in medical therapies.

His work integrates molecular biology with engineering approaches to address challenges in bone healing, dental tissue repair, and fibrosis. Key contributions include developing ultrasound-responsive scaffolds for controlled drug delivery and understanding genetic pathways (e.g., RUNX2, BMP signaling) critical for craniofacial development and fracture repair.

Recent studies highlight the role of DDR2 in skeletal progenitors and fibroblasts, with applications in lung fibrosis and bone regeneration. Franceschi’s research bridges basic science and translational medicine, leveraging interdisciplinary methods to advance regenerative technologies.