Reilly T. Enos

Reilly T. Enos, PhD, is an Assistant Professor in the Department of Pathology, Microbiology & Immunology at the University of South Carolina School of Medicine. His research focuses on the molecular mechanisms of sex differences in obesity, particularly metabolic and inflammatory processes influenced by sex steroids. The Enos Lab employs rodent models and advanced metabolic phenotyping to investigate menopause-related metabolic dysfunction and complementary therapies.

• PhD, Exercise Science (Applied Physiology), University of South Carolina, 2013
• Post-Doctoral, Complementary and Alternative Medicine in Cancer and Obesity, University of South Carolina School of Medicine, 2017
• MS, Exercise Physiology, Baylor University, 2009
• BS, Dietetics, University of Northern Colorado, 2010
• BA, Spanish & Physical Education, College of Wooster, 2007

Dr. Enos’s research spans immunometabolism, obesity, cancer cachexia, and gut microbiota. His work explores how dietary components (e.g., quercetin, emodin), hormonal status (especially estrogen), and immune modulation (e.g., miR-155, macrophages) influence metabolic and oncological outcomes. He investigates sex-specific responses to high-fat diets, inflammation, and therapeutic interventions using transgenic and diet-induced mouse models.

His recent publications highlight trends in metabolic physiology, inflammation, and cancer, often examining the interplay between adipose tissue, immune cells, and hormonal regulation. Key themes include the impact of vivarium conditions on reproducibility, the role of microRNAs in tumorigenesis, and the safety and efficacy of natural compounds.

Dr. Enos has not been awarded any listed scientific prizes or fellowships in the provided texts.

He advises a research team focused on metabolic and inflammatory disease models, frequently collaborating with researchers such as Erin A. Murphy and Kandy T. Velázquez. His lab receives funding for studies on obesity, cancer, and complementary medicine, though specific grants are not detailed. The lab is equipped for metabolic phenotyping and rodent model studies.

The Enos Lab is dedicated to understanding sex-specific metabolic regulation and developing targeted therapies for obesity and cancer-related metabolic disorders, with a focus on translational relevance and experimental rigor.