معرفی
Professor Ray Owens leads Protein Production UK (PPUK), a program within the Rosalind Franklin Institute focused on protein engineering and production at the University of Oxford. His work develops innovative methods for protein expression through the Oxford Protein Production Facility pipeline, with applications in structural biology and therapeutic development.
His research spans protein engineering, structural biology, and nanobody technology with particular emphasis on membrane protein production and stabilization. Using cryo-EM and advanced expression systems across microbial, insect, and mammalian cells, his team develops tools for structural analysis and therapeutic applications, especially targeting respiratory viral diseases.
His recent publications (2021-2023) demonstrate expertise across structural biology, virology, and protein engineering, with significant contributions to understanding membrane protein transport, SARS-CoV-2 neutralization, and bacterial biofilm mechanisms. The work shows a clear trajectory toward therapeutic applications of structural insights.
Professor Owens mentors student Matthew Tang and collaborates extensively across structural biology and virology research domains. His work receives support through the Rosalind Franklin Institute's Structural Biology theme, enabling partnerships with both academic groups and industry for technology development and translation.
His laboratory specializes in nanobody generation for membrane protein stabilization and develops diagnostic/therapeutic binding agents for respiratory viral diseases, operating at the intersection of academic research and clinical applications.
