معرفی
Dr. Pradeep Manuneedhi Cholan is a Research Fellow at Macquarie Medical School, affiliated with the Motor Neuron Disease Research Centre at Macquarie University. He specializes in molecular and medical research with a focus on zebrafish models to investigate microbiome effects on cardiovascular health, inflammation, and neurological disorders. His work bridges microbiology, immunology, and genetics to address hyperlipidaemia, oxidative stress, and Alzheimer's disease mechanisms.
- Research Interests: Zebrafish models, gut microbiome interactions, hyperlipidaemia, microbial signaling, neurodegenerative diseases, and inflammatory pathways.
- Recent Projects: Active in studying gut microbiome impacts on microglial cells in Alzheimer's disease (2024-2027).
His research outputs (14 articles from 2017-2025) emphasize translational studies using zebrafish larvae to model human conditions like diet-induced metabolic disorders and cigarette smoke toxicity. Key findings include anti-inflammatory roles of butyrate and MyD88-dependent pathways in hyperlipidaemia progression.
- Notable Awards: Wiley-Biofactors Young Investigator Award (2022), Student Travel Award (2016).
- Grants/Projects: Leads a 2024-2027 project on Alzheimer's microbiome research.
He collaborates with institutions globally to advance understanding of microbiome-cardiovascular-neurological crosstalk, with media coverage highlighting breakthroughs in zebrafish-based Alzheimer's research.
