Pim de Vink

Pim de Vink is a doctoral researcher at Eindhoven University of Technology, affiliated with the Biomedical Engineering department and Chemical Biology group. Supervised by dr. L.-G. Milroy and prof. L. Brunsveld, his work bridges supramolecular chemistry and chemical biology, focusing on host/guest chemistry for protein complex modulation.

Education:

• B.Sc. in Chemistry (2014) from University of Amsterdam
• M.Sc. in Biomedical Engineering (2016) from TU/e
• Internship at Max Planck Institute for Molecular Physiology (2016) on gold-catalyzed synthesis

Research Themes: His research develops switchable cucurbituril-based systems for light-controlled enzyme activation and artificial signaling networks. Key areas include protein-protein interaction stabilization, thermodynamic modeling, and allosteric nuclear receptor modulation.

Publication Trends: Across JACS, Chemical Science, and RSC Chemical Biology, his work from 2017–2023 emphasizes supramolecular tools for biochemical applications. Notable contributions include 100-fold affinity enhancement of 14-3-3 ligands and UV-responsive cucurbituril release mechanisms.

Grants: Funded by Netherlands Organization for Scientific Research (NWO) through Gravity program 024.001.035 and VICI grant 016.150.366.