
معرفی
Philip Woodman is a Professor of Cell Biology and Head of the Division of Molecular & Cellular Function at the University of Manchester. His research focuses on understanding how growth factor receptors are regulated through membrane trafficking pathways, particularly the role of endosomes and lysosomes in signaling termination and disease. He leads projects investigating the molecular mechanisms of receptor downregulation, endosomal sorting, and the interplay between endosome motility and signaling. His work contributes to UN Sustainable Development Goal 3 (Good Health and Well-being) through studies on cancer and cellular dysfunction.
Key research areas include epidermal growth factor receptor (EGFR) trafficking, ubiquitination-driven sorting, and the role of motor proteins like dynein in endosomal dynamics. Collaborative projects include studies on cellular dynamics and compartmentalisation, protein function via mass spectrometry, and TGF-beta activation pathways. He has supervised 11 research students and holds grants focused on membrane trafficking mechanisms and their biomedical applications.
- Education: BSc, PhD (specific institutions not listed)
- ORCID: 0000-0001-9497-1235
His lab explores how endosomal sorting ensures proper receptor degradation versus recycling, with implications for cancer therapy and viral infection. Recent work highlights ESCRT machinery, LINC complex interactions, and the spatial regulation of signaling pathways via endosome motility.
Philip Woodman در سایتهای دیگر
جستوجوهای مرتبط
شاید اینها هم برایتان مناسب باشند
Paul WhitleyUniversity of Bath · مدرس ارشد
Paula RowSwansea University · مدرس ارشد
Markus BabstUniversity of Utah · استاد- MMartin BaronThe University of Manchester · مدرس ارشد
Colin HopkinsGraz University of Technology · استاد- JJeanette Carolina Moulinier AnzolaUniversity of Natural Resources and Life Sciences Vienna · پژوهشگر