معرفی
Prof Philip Biggin is a Professor of Computational Biochemistry at the University of Oxford and an Ord Fellow and Tutor at Lady Margaret Hall (LMH). He directs the DPhil in Computational Discovery Programme, having joined Oxford with a lectureship and RCUK Fellowship in 2007, becoming a Fellow and Tutor in Biochemistry in 2012 before promotion to full Professor in 2016.
His research centers on protein dynamics and drug design, employing computational tools to unravel ligand-binding mechanisms and conformational changes in proteins. This work—conducted in collaboration with pharmaceutical companies—aims to enable rational drug design, leveraging local computational resources and the HECBioSim Consortium's ARCHER supercomputer. As a founder of CCPBioSim, he advances collaborative biomolecular simulation infrastructure.
Recent publications demonstrate expertise in molecular dynamics simulations of ion channels, receptors, and drug-target interactions, with applications spanning neuropharmacology, toxicology, and computational method development. Key themes include nerve agent antidote design, serotonin receptor activation, and ion channel dynamics.
His notable achievements include:
- University Excellence in Teaching Award (2011) for innovative Computational Biochemistry and Bioinformatics curricula
- RCUK Fellowship (2007)
As Director of the DPhil programme, Prof Biggin advises graduate students while leading the Biggin Lab. His group maintains industry partnerships and contributes to major computational consortia, driving advancements in rational drug design through cutting-edge biomolecular simulation.
