Ulrich Zachariae

Professor Ulrich Zachariae is a Professor of Molecular Biophysics at the University of Dundee, affiliated with the School of Life Sciences and the Biological Chemistry and Drug Discovery department. He obtained his PhD in 2004 from the Max Planck Institute for Biochemistry and held postdoctoral roles at the Max Planck Institute for Biophysical Chemistry before transitioning to industry at AstraZeneca.

His research focuses on membrane protein function, particularly ion channels and cell surface receptors, and employs computational methods such as molecular simulations and data-driven approaches to combat antimicrobial resistance. Recent work includes elucidating ion selectivity mechanisms, improving antibiotic bioavailability, and developing tools like State-Specific Information (SSI) to analyze protein-water dynamics.

Key trends in his publications span biomolecular simulations, computational drug discovery, and structural biology, with a strong emphasis on ion channels and GPCRs in 2025, antimicrobial resistance in 2024, and foundational work on K+ channels in 2018.

Professor Zachariae leads the MSc in Biological Data Science program and contributes to teaching modules in Biomolecular Structure and Interactions. His collaborations include institutions like St Andrews University and Trinity College Dublin, with funding from the Biotechnology and Biological Sciences Research Council (BBSRC).