معرفی
Peter Park is a Professor of Biomedical Informatics at Harvard Medical School and Director of its Bioinformatics and Integrative Genomics (BIG) PhD program. His research focuses on computational analysis of genomic data, particularly in cancer genomics, somatic mosaicism, and epigenetic mechanisms. He leads major projects like the Somatic Mosaicism across Human Tissues (SMaHT) network and contributes to consortia such as The Cancer Genome Atlas (TCGA) and ENCODE. His work integrates advanced computational methods with clinical applications, aiming to advance precision medicine and understand genetic drivers of disease.
Education:
- B.A. in Applied Mathematics, Harvard University
- Ph.D. in Applied Mathematics, California Institute of Technology
- Postdoctoral studies in biostatistics, focusing on molecular biology and genetics
Research Interests:
His lab develops algorithms for genomic data analysis, including methods for detecting copy number variations, mutational signatures, and structural variations. Key areas include cancer genomics, somatic mosaicism in neurodegenerative diseases, and 4D nucleome structure-function relationships. He emphasizes translational research, applying computational tools to clinical problems like tumor evolution and drug response prediction.
Funding & Grants:
- NIH grants (e.g., R01HG012573, R01CA269805)
- Funding from Mark Foundation, Simons Foundation, and Chan Zuckerberg Initiative
- Principal Investigator for multiple collaborative projects
Labs & Teams:
The Park Lab collaborates with interdisciplinary teams in computational biology, oncology, and neuroscience. Current projects include developing tools for single-cell DNA sequencing analysis and exploring mutational signatures in cancer and neurodegenerative disorders.
