Peter L J de Keizer

Peter L J de Keizer is an Associate Professor at the University Medical Center Utrecht, specializing in cellular senescence and cancer biology. His work focuses on leveraging senescence mechanisms for therapeutic applications in oncology and aging-related diseases. Contact: pkeizer@umcutrecht.nl

Research Interests:

• Molecular regulation of cellular senescence
• Senolytic compounds targeting p53-FOXO4 interactions
• Translational applications in cancer (especially brain metastasis) and musculoskeletal diseases
• Immunosenescence in tumor microenvironments
• Development of aging biomarkers

Publication Trends: Recent works span structural biology of p53 domains (2025), geriatric frailty metrics (2025), senescence in cartilage models (2025), and immunotherapy repositioning (2024). Key intersections involve senescence biology, cancer-immune interactions, and aging-related pathologies.

External Engagement: Founder and Managing Director at Cleara Biotech B.V., translating academic findings into biotech applications.