Peck Y. Ong

Peck Y. Ong, MD, serves as Associate Professor of Clinical Pediatrics at the University of Southern California and practices at Children's Hospital Los Angeles. Board-certified in Allergy and Immunology, he leads as site Principal Investigator for the Atopic Dermatitis Research Network in Los Angeles, focusing on complex cases where atopic dermatitis coexists with food allergies and asthma.

Dr. Ong's research centers on atopic dermatitis pathogenesis, particularly skin barrier dysfunction, microbial interactions, and innate immunity defects. His seminal 2002 New England Journal of Medicine paper demonstrating low defensin levels in atopic dermatitis patients remains among the most cited works in the field. Current investigations span biomarker discovery (e.g., CERS1 for Staphylococcus aureus colonization), health disparities in eczema assessment, and mental health integration for atopic dermatitis patients.

• Research Trends: Recent publications (2023-2025) emphasize precision medicine approaches, systemic immunomodulator safety (particularly dupilumab), genetic contributions to disease severity, and real-world applications of germline testing in Asian populations.
• Clinical Focus: Integrates latest research on skin barrier protection, microbial management, and mental health support into patient care for complex atopic conditions.

Professional Recognition

• Diplomate, American Board of Allergy and Immunology
• Principal Investigator, Atopic Dermatitis Research Network (Los Angeles site)

Dr. Ong actively contributes to national guideline development including the 2023 Atopic Dermatitis Guidelines and EAACI Biologicals Guidelines. His work bridges clinical practice with translational research through collaborations with the Southern California research community, focusing on improving outcomes for children with severe atopic conditions. Current efforts include developing objective severity metrics for diverse skin types and optimizing mental health support systems for eczema patients.