معرفی
Dr. Paulo Ribeiro serves as Reader (equivalent to Associate Professor) in Cell and Developmental Biology and Group Leader at the Centre for Tumour Biology, Queen Mary University of London. His research employs Drosophila melanogaster to investigate molecular mechanisms governing tissue growth, invasion, metastasis, and tumour heterogeneity.
His research spans Cancer Biology, Cell Signaling, Developmental Biology, and Drosophila Genetics, with emphasis on Hippo pathway regulation. Key investigations include spatial control of Hippo signaling, cytoskeletal interactions, and protein degradation mechanisms through ubiquitin ligases and phosphatases, revealing fundamental cancer-relevant growth control processes.
Recent publications (2010-2019) demonstrate consistent focus on Hippo pathway modulation, particularly through Spectrin cytoskeleton, Crumbs polarity complex, and PP2A regulatory networks. These studies leverage Drosophila genetics to uncover conserved mechanisms applicable to human tumourigenesis and metastasis.
Professional engagements include:
- European Association of Cancer Research
- British Association of Cancer Research
- Biochemical Society
- Independent Scientific Advisory Panel for Bone Cancer Research Trust
Secured major funding includes BBSRC Project Grant (2020-2023; £649,038) for 'A PP2A regulatory nexus modulating Hippo signalling and growth' and Barts Charity Large Project Grant (2017-2021; £237,344) for 'OncoChrome: A genetic system to study and exploit tumour heterogeneity'. His research group operates within the Centre for Tumour Biology's collaborative cancer research environment.
