Paul Micevych

Dr. Paul Micevych is a Professor at the University of California, Los Angeles, affiliated with the Brain Research Institute. His research spans neurobiology, endocrinology, and reproductive physiology, focusing on estrogen and progesterone signaling in the central nervous system.

• Email: pmicevych@mednet.ucla.edu

His lab investigates membrane estrogen receptor dynamics in neurons and glia, estrogen's role in neuroprotection for Parkinson’s disease, and neurosteroid biosynthesis in hypothalamic astrocytes. Key mechanisms include G protein-coupled receptor interactions, calcium signaling, and opioid pathway modulation of sexual behavior.

Recent work highlights 2025 studies on mouse visceromotor cortex networks and 2022 breakthroughs in hypothalamic progesterone synthesis during puberty. Collaborative projects explore neuroendocrine circuit integration and steroid receptor trafficking in reproductive behavior.

Scientific awards and honors not explicitly mentioned in the text.

Current research in the Micevych Laboratory (CHS, Los Angeles) combines RT-PCR, calcium imaging, and optogenetics to dissect estrogen's rapid signaling effects on dopamine neuroprotection and nociceptive pathways. The lab also studies kisspeptin neuron interactions and neuroprogesterone's role in the luteinizing hormone surge.