معرفی
Dr. Paul Klotman is a Professor at Baylor College of Medicine, leading research on HIV-associated nephropathy (HIVAN) and renal responses to HIV infection. His work focuses on the direct infection of kidney epithelium by HIV, the role of Podocan in renal fibrosis, and MYH9 genetic variation as a susceptibility factor for HIVAN.
- Key Research Areas: HIVAN pathogenesis, viral reservoirs, extracellular matrix biology, genetic predisposition to renal disease
- Collaborators: Debbie Hyink (BCM), John Cijiang He (Mount Sinai), Mary Klotman (Duke), Avi Ma’ayan (Mount Sinai)
His laboratory's publications demonstrate expertise in virology, nephrology, and molecular genetics. Collaborative efforts extend to institutions like Duke University and Mount Sinai, with implications for global health policy as HAART therapy expands in Africa. Research trends include mechanistic studies of HIV-induced renal damage and translational applications for early diagnosis.
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