Paul Curley

Paul Curley serves as Lecturer in Biochemistry at the University of Westminster since 2000, with prior research appointments at University of Manchester (Sanofi-Aventis project), Dublin City University, University of Calgary, and University of Notre Dame. His academic foundation includes BSc (1985) and PhD (1989) in Biochemistry from University College Dublin, where he investigated flavodoxin structure-function under Prof. Stephen Mayhew.

His research program spans computational protein modeling, lectin-carbohydrate interactions in cancer, autophagy mechanisms in Trichomonas vaginalis, and melanocortin peptide therapeutics for osteoarthritis. The Cell Communication research group employs integrated biochemical, biophysical, and computational approaches to study disease mechanisms at molecular levels, with strong emphasis on translational applications.

Analysis of his 2005-2014 publications reveals an evolving focus from integrin pharmacology to cancer glycobiology and osteoarthritis therapeutics, characterized by methodological innovation like biosensor-based affinity measurements and consistent interdisciplinary collaboration. His work appears in high-impact journals including Biochemical Pharmacology and Journal of Biological Chemistry.

Scientific recognition:

• Member of the Biochemical Society
• No major awards specified in available documentation

He currently supervises research student Hans Heindl and previously guided Karima Brimah to doctoral completion on Fusobacterium necrophorum. His funding history includes industry collaboration (Sanofi-Aventis) and likely continues through research council grants in computational biochemistry and disease mechanisms. As part of the Tissue Architecture and Regeneration Research Group, his lab fosters collaborative projects bridging basic science and clinical applications in cancer and joint disorders.