معرفی
Pau Castel, PhD, serves as Assistant Professor in the Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine (New York University). His research focuses on molecular mechanisms of cancer, particularly RAS signaling pathways and RASopathies, with laboratory facilities at 450 East 29th Street, New York.
His academic background includes:
- PhD from University of Barcelona
- Postdoctoral training at University of California San Francisco (Frank McCormick Lab)
Dr. Castel's research spans cancer biology, molecular pharmacology, and genetic disorders. He investigates oncogenic transformation mechanisms, protein regulation (including deubiquitination by USP9X), and therapeutic targeting in lung adenocarcinoma, breast cancer, and syndromes like Noonan and Costello. His work bridges structural biology with clinical applications to develop precision oncology approaches.
Analysis of his 2022-2025 publications reveals consistent focus on RAS pathway dysregulation, with emphasis on RIT1 protein function across multiple disease contexts. His research demonstrates strong international collaboration, particularly through RASopathies symposia, and integrates molecular, structural, and clinical methodologies to identify novel therapeutic vulnerabilities in cancer and developmental disorders.
No scientific awards were mentioned in the provided text.
No information regarding student advising or research grants was provided in the available materials.
Dr. Castel leads a research laboratory at NYU Langone Health investigating cancer signaling pathways, though specific team composition and project details were not disclosed in the source materials.
