Paolo Lusso

Paolo Lusso serves as Chief of the Viral Pathogenesis Section within the Laboratory of Immunoregulation at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and holds an affiliate faculty appointment in the School of Systems Biology.

His research centers on viral pathogenesis mechanisms, with deep focus on virology and immunology intersecting with systems biology approaches. Dr. Lusso investigates host-pathogen interactions, viral immune evasion strategies, and molecular determinants of disease progression using interdisciplinary methodologies that integrate computational modeling with experimental virology.

Leading the Viral Pathogenesis Section, he directs a research team studying viral infection dynamics, particularly in retroviruses and emerging pathogens, emphasizing translational applications for therapeutic development. His work bridges fundamental virology with clinical immunology to address complex infectious disease challenges.