Pallav Kosuri

Pallav Kosuri is an Assistant Professor at the Salk Institute for Biological Studies, holding the Hearst Foundation Developmental Chair. His research focuses on understanding biological function through molecular movements, from single molecules to organs. He leads the Integrative Biology Laboratory, developing nanoscale DNA devices like ORBIT rotors to study molecular rotations and creating 3D molecular atlases of the heart to address heart failure mechanisms.

Education: PhD in Biochemistry and Molecular Biophysics from Columbia University (advisor Julio Fernandez), MSc in Engineering Physics from KTH Royal Institute of Technology, and postdoctoral work at Harvard University with Xiaowei Zhuang. His innovations include ORBIT technology, specialized AFM instrumentation, and the NanoNERF DNA origami project.

Research tracks span molecular-scale studies of transcription and gene editing, ensemble-scale synthetic muscle models, and organ-scale heart disease analysis using spatial transcriptomics. Collaborations include Salk’s Gage Lab and Mark Rober’s team for public science outreach. Awards include the 2024 W.M. Keck Foundation Award and 2022 Beckman Young Investigator Award.

Lab members include postdocs Yuening Liu and Brian Tenner, PhD students Ryan Fantasia and Amanda Wacker, and computational specialist Deevanshu Goyal. Current projects aim to connect molecular biomechanics to clinical applications, with a focus on regenerative therapies for heart failure and high-resolution imaging innovations.