معرفی
Pablo Fernandez Tussy is an Associate Research Scientist in the Department of Comparative Medicine at Yale School of Medicine. He holds a PhD from the University of the Basque Country and completed postdoctoral training at Yale under Dr. Carlos Fernandez-Hernando. His research focuses on the role of microRNAs in lipid metabolism, obesity, and fatty liver disease, with a current emphasis on sterols in metabolic and immune processes.
- Education:
- BS (Honors) in Genetics, University Complutense de Madrid
- MS, PhD in Molecular Biology, University of the Basque Country/CIC bioGUNE
Research Interests: Dr. Fernandez Tussy investigates microRNA regulation of lipid metabolism, particularly miR-33’s roles in obesity, fatty liver disease, and hepatocellular carcinoma. His work integrates molecular biology, genetics, and systems biology to uncover mechanisms linking metabolism and immunity. Recent studies highlight miR-33’s control of hunger signaling in hypothalamic neurons and its therapeutic potential in liver cancer.
His publications (2024–2019) emphasize miR-33’s roles in NAFLD progression, ferroptosis-driven tumor suppression, and metabolic signaling pathways. Awards include a 2023 American Heart Association Career Development Award to advance his independent research.
- Awards:
- American Heart Association Career Development Award (2023)
- Basque Country Postdoctoral Fellowships (2020–2019)
He collaborates with leading labs at Yale and internationally, contributing to interdisciplinary teams studying metabolic and immune disorders. His work bridges basic science and translational medicine, with implications for novel therapies targeting miRNA pathways.