Pablo E. Visconti

Pablo E. Visconti serves as Professor in the Department of Veterinary and Animal Sciences at the University of Massachusetts Amherst, where his laboratory investigates the molecular basis of sperm capacitation—a prerequisite for fertilization.

• Ph.D., University of Buenos Aires, 1991
• Postdoctoral Training, University of Pennsylvania

His research centers on intracellular signaling pathways during sperm capacitation, with emphasis on tyrosine phosphorylation dynamics, cholesterol removal mechanisms, and cAMP-dependent regulation via protein kinase A. Using mouse models, his work elucidates how bicarbonate and calcium influx trigger hyperpolarization and phosphorylation cascades essential for fertilizing capacity.

Dr. Visconti leads an active research program focused on identifying key protein substrates, kinases, and phosphatases involved in capacitation, while exploring spatial regulation of signaling events within sperm subcellular compartments. His findings have significant implications for infertility treatments and contraceptive development.