معرفی
Owen Williams is a Professor of Cancer Biology at the University College London (UCL), affiliated with the Developmental Biology and Cancer Department within the UCL GOS Institute of Child Health. His research focuses on understanding the molecular mechanisms driving pediatric acute leukemia, particularly chromosomal translocations and drug resistance.
- Co-Leader and Lecturer, MSc module CHLD0071: Molecular and Clinical Aspects of Childhood Cancers
- Lecturer, 3rd-year undergraduate module CINS0012: Paediatric and Young Adult Cancer: Basic Research and Clinical Applications
Research Overview: Williams’ group investigates chromosomal translocations in pediatric leukemia, focusing on fusion genes like KMT2A (MLL) and ETV6-RUNX1. His work aims to translate molecular insights into novel targeted therapies, including drug repositioning and protein degradation strategies, to improve outcomes for high-risk leukemias.
Publication Trends: His recent research emphasizes KMT2A-rearranged leukemias, c-MYB regulation, and drug repositioning for pediatric cases. Key subfields include protein degradation, transcriptional oncogenes, single-cell genomics, and chemoresistance mechanisms.
Group Members:
- Post-Doctoral Fellows: Clemence Virely, Noelia Che, Olivia Ciampa
- PhD Students: Harsh Bumia, Danesh Sundar
