معرفی
Hesta McNeill is a researcher affiliated with Newcastle University, contributing to leukemia and cancer biology through molecular studies. Her work focuses on epigenetic regulators, fusion genes (e.g., RUNX1/ETO, MLL/AF4), and mechanisms of treatment resistance in hematological malignancies.
- Institutions: Newcastle University
- Roles: Researcher
Research spans:
- Epigenetic control of leukemogenesis
- Transcriptional and chromatin dynamics in AML and ALL
- Development of hiPSC-based models for drug screening
- Role of angiopoietin1 in MLL-rearranged ALL
- Heat shock factor-1 interactions with p53 in DNA damage
- MDM2 inhibitors in prostate cancer therapy
Publications highlight collaborations with Professors Vasily Grinev, Olaf Heidenreich, and others, emphasizing genome-wide approaches (RNAi, transcriptomics) and cancer stem cell dynamics. No specific awards, students, or part-time status are documented in the source data.
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