معرفی
Ning Xu Landén is a Senior Lecturer (Docent) at Karolinska Institutet, leading the Skin Wound Healing Research Group within the Department of Medicine, Solna. Her research focuses on decoding the molecular logic of skin repair and radiation injury to develop next-generation therapies. She has established herself as a leading researcher in the field of wound healing, with particular expertise in non-coding RNA biology and single-cell genomics.
- Karolinska Institutet, Senior Lecturer (2022-present)
- Karolinska Institutet, Docent in Experimental Dermatology (2017)
- Established research group as Assistant Professor (2014)
- Postdoctoral research at Karolinska Institutet (2009-2013)
Dr. Xu Landén's research spans four interconnected themes: building molecular atlases of human wound healing using single-cell and spatial transcriptomics; investigating regulatory RNAs in skin repair; developing RNA-based regenerative therapies; and studying radiation memory and late tissue injury. Her work has identified key non-coding RNA regulators of wound healing and revealed how radiation creates epigenetic memory in skin cells that impairs healing in cancer survivors.
Analysis of her most recent publications reveals a strong focus on single-cell genomics approaches to understand wound healing at unprecedented resolution, with particular emphasis on non-coding RNA networks including microRNAs, long non-coding RNAs, and circular RNAs. Her research increasingly integrates multi-omics approaches to identify therapeutic targets for chronic wounds and radiation-induced tissue damage.
- LEO Foundation Award for outstanding contributions to dermatology research
Dr. Xu Landén leads a dynamic research group with multiple PhD students, postdoctoral researchers, and collaborators. Her group has secured significant funding from the Swedish Research Council, Cancerfonden, Ragnar Söderbergs Foundation, Welander and Finsens Foundation (Hudfonden), LEO foundation, and Karolinska Institutet. Her research bridges fundamental discovery with clinical applications, with a focus on translating RNA discoveries into novel treatments for hard-to-heal wounds.
The Skin Wound Healing Research Group maintains an active research platform that integrates molecular biology, advanced genomics, and direct access to patient materials. Their work has led to the development of an interactive wound atlas that serves as a community resource for exploring human wound biology.
