معرفی
Nikola Pavletich, PhD, holds the Stephen and Barbara Friedman Chair at the Memorial Sloan Kettering Cancer Center (MSKCC) within the Structural Biology Program. He earned his PhD from The Johns Hopkins University School of Medicine (1991) and BS from California Institute of Technology (1988).
- Research focuses on structural biology of cancer-related pathways, including DNA repair mechanisms, mTOR signaling, and Fanconi Anemia pathway.
- Key contributions include elucidating homologous recombination, mTOR kinase structure, and FAN1 nuclease function.
His work bridges structural insights with therapeutic potential, particularly in cancer. Notable awards include HHMI Investigator (Howard Hughes Medical Institute) and membership in the National Academy of Sciences.
Lab collaborations involve projects like the Tri-Institutional TPCB Program, focusing on postdoctoral training in cancer biology. His team investigates pathways controlling cell growth and genomic integrity, with applications in drug design and disease mechanisms.
