معرفی
Neal Rosen, MD, PhD is a leading pharmacologist and breast medical oncologist at Memorial Sloan Kettering Cancer Center (MSKCC), holding the Enid A. Haupt Chair in Medical Oncology. His research focuses on understanding oncogenic signaling pathways and developing mechanism-based cancer therapies.
- Education: MD and PhD from Albert Einstein College of Medicine
- Lab Affiliations: Molecular Pharmacology Program, Center for Experimental Therapeutics, Tri-Institutional PhD Program in Chemical Biology
Research Interests center on:
- Signal Transduction in human cancers, particularly RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways
- Kinase Inhibitors for BRAF, MEK, mTOR, and Hsp90
- Translational Oncology bridging molecular mechanisms to clinical applications
- Drug Resistance in BRAF and KRAS mutant tumors
Article Trends reveal a focus on kinase inhibitors targeting ERK, PI3K, and Hsp90 pathways, with emphasis on mutation-specific therapies and combination strategies for overcoming resistance.
Lab Alumni include prominent researchers like David Solit (MSKCC), Poulikos Poulikakos (Mount Sinai), and Qing-Bai She (University of Kentucky). His scientific disclosures involve equity and consulting roles with companies like BeiGene and Kura Oncology.
