معرفی
Niklas Mattsson-Carlgren serves as an Associate Professor and Senior Lecturer at Lund University's Faculty of Medicine, Department of Clinical Sciences. He holds multiple significant roles including Deputy Research Team Manager and Principal Investigator for several major research projects. His affiliations extend to the Wallenberg Centre for Molecular Medicine (WCMM), LU Profile Area: Proactive Ageing, and MultiPark: Multidisciplinary Research Focused on Parkinson's Disease.
Dr. Mattsson-Carlgren's research primarily focuses on Alzheimer's disease and other neurodegenerative conditions, with additional work on acute brain injuries such as those following cardiac arrest. His expertise spans neurochemistry, including the regulation of pain and sleep. He employs biochemical measurements, neuroimaging, and cognitive testing to study disease processes in vivo across the spectrum from preclinical disease to advanced dementia. His work aims to improve diagnostic and prognostic methods in clinical practice, enhance clinical trial design for novel therapies, and deepen understanding of disease mechanisms.
His recent publications demonstrate a strong emphasis on plasma biomarkers for Alzheimer's disease detection and monitoring, with particular focus on tau and amyloid pathology. The research shows increasing integration of machine learning approaches with traditional biomarker analysis, reflecting a trend toward more sophisticated diagnostic tools that combine multiple data sources for improved accuracy in predicting disease progression.
As Principal Investigator for multiple significant projects including 'Longitudinal plasma biomarkers, cognitive data and amyloid PET to improve early prevention of Alzheimer's disease' and 'Validation of an MTBR tau immunoassay for CSF and plasma,' he leads substantial research efforts funded by organizations including Familjen Rönströms stiftelse, Eli Lilly and Company, and the Knut and Alice Wallenberg Foundation. He also serves as supervisor for PhD students, notably for 'Studies of induced neuronal cells in Alzheimer's disease.'
Dr. Mattsson-Carlgren is actively involved in the neuroscience community, serving on the program committee for Neuroscience Day 2025. His research contributes to UN Sustainable Development Goals related to health and wellbeing. His work has gained significant attention, with multiple papers being picked up by news outlets and referenced across social media platforms including X (Twitter) and Bluesky.
