Charlotte Teunissen

Charlotte Teunissen is a Full Professor in Neurochemistry at Vrije Universiteit Amsterdam, affiliated with Amsterdam UMC. She leads the Neurochemistry Laboratory and directs the body fluid program at the Alzheimer Center Amsterdam. Her international leadership includes coordinating the CSF Society, Alzheimer Association-Global Biomarker Standardization consortium, and Coral proteomics consortium.

Her research centers on developing body fluid biomarkers for neurological diseases, spanning identification, assay development, clinical validation, and implementation in patient care. Key focus areas include Alzheimer's disease diagnosis, stratification, prognosis, and treatment monitoring through neurodegeneration, neuroinfection, and neuroinflammation pathways. This translational work bridges laboratory science and clinical neurology to improve neurological disease management.

Recent publications demonstrate concentrated efforts on Alzheimer's biomarkers, particularly CHIT1/DDAH1 for amyloid imaging abnormalities, dementia prevention pathways via cohort studies, and multiphosphorylated tau detection in cerebrospinal fluid/plasma. These studies reveal a cohesive trajectory toward minimally invasive diagnostics, risk profiling, and therapeutic monitoring with strong emphasis on clinical applicability.

Professor Teunissen coordinates the Marie Curie MIRIADE project training 15 researchers in dementia biomarker development. Her leadership in the Alzheimer Center Amsterdam's body fluid program and international consortia drives global standardization efforts, while her neurochemistry laboratory serves as the operational hub for biomarker validation studies across multiple neurological conditions.