معرفی
Prof. Nathalie Grob is an Assistant Professor in the Department of Chemistry and Applied Biosciences at ETH Zürich, leading a research group focused on peptide-based drug discovery. Her work emphasizes therapeutic modulation of protein-protein interactions using combinatorial chemistry and mass spectrometry, with a specific focus on diseases affecting women's health. She holds a BSc and MSc in Pharmaceutical Sciences from the University of Basel and a PhD from ETH Zürich, followed by postdoctoral research at MIT under Prof. Bradley Pentelute.
Research interests include radiolabeled peptide development for cancer diagnosis/treatment, covalent peptide binders, and AI-driven small molecule discovery. Her group employs multidisciplinary approaches to develop robust drug discovery workflows, particularly targeting under-researched conditions relevant to women's health.
Key achievements include a Swiss National Science Foundation Starting Grant and contributions to tumor-targeting minigastrin analogs. Courses taught include Drug Seminar (535-0011-00L) and Seminars on Drug Discovery and Development (535-0900-00L).
Her research integrates chemical synthesis, molecular biology, and computational methods, with recent work published in high-impact journals. Current projects aim to advance peptide therapeutics through innovative design strategies and precision targeting mechanisms.
