Nancy C. Reich Marshall

Nancy C. Reich Marshall is a Professor in the Department of Microbiology and Immunology at Stony Brook University. She also serves as Past President of the International Cytokine & Interferon Society (ICIS) and is a Fellow of the American Association for the Advancement of Science (AAAS). Her laboratory investigates cytokine signaling pathways, particularly JAK-STAT mechanisms, and their roles in immune defense, viral infections, and cancer biology.

Her research focuses on:

• Molecular mechanisms of cytokine signaling in cancer (especially pancreatic cancer) and viral pathogenesis
• KRAS-driven tumorigenesis and immune evasion strategies
• Interferon responses in SARS-CoV-2 and other viral infections
• STAT transcription factor dynamics in cellular identity and disease

Analysis of her 15 most recent publications reveals strong emphasis on:

• KRAS/STAT3 interactions in pancreatic cancer progression
• Interferon-mediated immune defenses against viruses including SARS-CoV-2
• Novel mechanisms of oncogene dependency and therapeutic resistance
• Sex-specific pathology in viral infections

Her scientific awards include:

• Fellow of the American Association for the Advancement of Science (AAAS)
• Past President of the International Cytokine & Interferon Society (ICIS)

She has advised over 30 graduate students and postdoctoral researchers, including Stephen D'Amico, Alexei Petrenko, and Hui-Chen Foreman. Her lab employs murine models and molecular techniques to study KRAS signaling in pancreatic cancer and interferon responses to pathogens.