Myles Lewis

Professor Myles Lewis is a Professor of Precision Medicine & Rheumatology at Queen Mary University of London's William Harvey Research Institute (Faculty of Medicine and Dentistry). He specializes in autoimmune rheumatic diseases, particularly Systemic Lupus Erythematosus (SLE) and rheumatoid arthritis, with a focus on integrating bioinformatics and multi-omic data for precision medicine applications.

Education:

• Preclinical Medicine: University of Cambridge
• Clinical Medicine: University of Oxford

Research Interests: His work combines bioinformatics analysis with clinical research, focusing on:

• Ubiquitination pathways in autoimmune diseases
• Multi-omic data integration (RNA-Seq, genomics, proteomics)
• Machine learning for treatment prediction in rheumatoid arthritis
• Biomarker development for stratified medicine

Key Projects:

• Leader of bioinformatics/biostatistics group analyzing PEAC, R4RA, and STRAP studies
• Member of MRC MATURA, RA-MAP, and IMI 3TR consortia

Awards:

• Wellcome Trust Clinical Research Fellowship (2005)
• Arthritis Research UK Clinician Scientist Fellowship (2011)
• Lancet Prize for Clinician Scientists (2015)

Grants & Collaborations:

• Sponsors: NIHR, MRC, Versus Arthritis
• Cross-institutional collaborations: Manchester University, Edinburgh University, GSK

Labs & Teams:

• Head of bioinformatics group developing tools like shinyExprPortal
• Co-inventor of patents for rheumatoid arthritis biomarkers (licensed to Exagen Inc)