معرفی
Muralidhar Hegde is a Professor at Weill Cornell Medical College and Houston Methodist Research Institute, where he leads research in neurodegenerative diseases and DNA repair mechanisms. His work bridges cancer and neuroscience programs.
- Education: PhD (Biochemistry/Neurochemistry, University of Mysore, 2006), MS (Biochemistry, Karnataka University, 2000), BS (Chemistry/Biochemistry, Karnataka University, 1998).
Research focuses on DNA damage response in ALS, Parkinson’s, and stroke, investigating how transition metals (iron/copper) impair DNA repair via NEIL enzymes. Current projects explore TDP-43 protein aggregation and mitochondrial DNA repair in ALS/FTD, funded by NIH R01, ALS Association, and Melo Foundation.
His 15 most recent articles (2023–2025) highlight themes in mitochondrial dysfunction, genotoxicity, and therapeutic nanozymes. Key trends include mouse models and CRISPR/Cas9 applications.
- Scientific Awards: Career Cornerstone Award (Houston Methodist), ABAP Senior Scientist Award (2019), Director, Division of DNA Repair Research (2021), Distinguished Visiting Scientist (2016), Emerging Scientist Award (2013).
Dr. Hegde mentors PhD students and collaborates with institutions like UTMB and Texas A&M University. His lab (Hegde Lab) investigates genome repair and neuroregeneration.
