معرفی
Mohsin Khan, PhD, is an Associate Professor in the Department of Cardiovascular Sciences at the Lewis Katz School of Medicine, Temple University. He leads the Center for Metabolic Disease Research, focusing on cardiac regeneration and metabolic signaling. His work integrates stem cell biology, exosome-mediated communication, and epigenetic reprogramming to address cardiac repair deficits in aging/diabetes.
Education:
- PhD in Molecular Biology, National Center of Excellence in Molecular Biology, Lahore (2008)
- MS in Zoology, Government College University, Lahore (2002)
- BS in Biological Sciences, Forman Christian College, Lahore (2000)
Research Interests: Dr. Khan’s lab investigates neonatal cardiac repair mechanisms, embryonic microRNA signaling, and diabetes-induced cardiac dysfunction. Key projects include:
- Reactivation of embryonic factors to enhance adult heart repair
- Exosome-based therapies using stem cell-derived vesicles
- Metabolic regulation in cardiac progenitor cells
- Age-related epigenetic changes in heart repair capacity
Publications: Over 80 peer-reviewed articles focus on miRNA regulation, exosome therapies, and metabolic-cardiac crosstalk. Recent work highlights LIN28A-driven regeneration and UCP2-mediated metabolic reprogramming.
Honors:
- American Association for Cancer Research (AACR)
- American Association for the Advancement of Science (AAAS)
Advising & Grants: Ongoing NIH-funded projects explore exosome-based cardiac repair and diabetes-cardiac axis modulation. Collaborations include Temple’s Institute of Regenerative Medicine and Engineering.
Labs/Teams: Leads a multidisciplinary team at the Center for Metabolic Disease Research, collaborating with immunologists, bioengineers, and computational biologists to advance regenerative therapies.
