معرفی
Zhongjian Cheng, PhD, is an Assistant Professor in the Department of Cardiovascular Sciences at Temple University's Lewis Katz School of Medicine. His research focuses on diabetes-mediated cardiovascular complications, particularly the mechanisms of vascular injury, endothelial dysfunction, and myocardial repair. He investigates extracellular vesicles/exosomes from diabetic cells and their modification via genetic, epigenetic, and metabolite approaches to enhance regenerative properties.
- Education: PhD from University of Helsinki; Postdoctoral fellowship at University of Calgary
- Affiliation: Member of the Aging + Cardiovascular Discovery Center
Dr. Cheng's work spans diabetic cardiovascular complications, extracellular vesicle biology, epigenetic modifications, and non-coding RNA (circular RNA, miRNA). His studies use animal models to explore vascular relaxation impairments, myocardial infarction, and heart failure mechanisms.
His recent publications highlight exosome-based therapeutics for heart failure, epigenetic sex differences in cardiac repair, and circRNA/miRNA roles in macrophage and endothelial cell function. Key awards include multiple American Heart Association grants.
