معرفی
Laurie A. Boyer is a Professor of Biology and Biological Engineering at the Massachusetts Institute of Technology (MIT), affiliated with the Koch Biology Building. She serves as Co-Undergraduate Officer and leads research on gene regulatory mechanisms in heart development and regeneration using embryonic stem cells and mouse models. Her work integrates genomic, genetic, biochemical, and cell biological approaches to understand chromatin dynamics and lineage commitment, with applications in cardiac tissue engineering and regeneration.
Education:
- PhD, 2001, University of Massachusetts Medical School
- BS, 1990, Biomedical Science, Framingham State University
Research Interests:
Dr. Boyer’s research focuses on the interplay between chromatin remodeling, epigenetic regulation, and transcriptional networks that drive heart development. She investigates how ATP-dependent chromatin remodelers influence lineage specification and explores methods to stimulate cardiac regeneration. Her lab combines advanced genomic techniques with tissue engineering to model 3D cardiac architecture, aiming to uncover regulatory circuits underlying normal and diseased heart development.
Publications:
Her recent work includes breakthroughs in high-throughput expansion microscopy for scalable super-resolution imaging, metabolic modulation of mesenchymal stem cells for cartilage repair, and the role of long noncoding RNAs like Braveheart in cardiovascular lineage commitment. These studies span molecular mechanisms of chromatin dynamics to translational applications in regenerative medicine.
Awards & Honors:
- Pew Scholars Award in the Biomedical Sciences (2008)
- Smith Family Award for Excellence in Biomedical Science (2009)
- Scientific American World’s 50 Top Leaders in Research (2006)
- Irvin and Helen Sizer Career Development Award (2012)
Grants & Collaborations:
Dr. Boyer oversees grants from organizations like the NIH and American Heart Association. She collaborates with teams on interdisciplinary projects, including tissue engineering and stem cell therapies. Her lab also develops innovative microscopy techniques to advance cellular imaging scalability.
Labs & Teams:
Her laboratory at MIT’s Koch Institute integrates computational biology, bioengineering, and molecular biology. The lab focuses on translating fundamental discoveries into clinical applications for heart disease and regeneration.
