معرفی
Mohan Doss is a Professor at Fox Chase Cancer Center, part of the Temple University Health System, where he conducts advanced research in nuclear medicine and medical physics, focusing on PET imaging and radiation dosimetry. He is affiliated with the Department of Radiology and plays a key role in developing and evaluating novel PET imaging agents.
- BSc in Physics, Madras University, 1971
- MSc in Physics, Indian Institute of Technology, Kanpur, 1973
- MS in Physics, Carnegie-Mellon University, 1975
- PhD in Physics, Carnegie-Mellon University, 1980
- Certified Member, Canadian College of Physicists in Medicine (Nuclear Medicine Physics), 1994
Dr. Doss's research centers on PET imaging, particularly in cancer staging and treatment monitoring. His work includes biodistribution and radiation dosimetry of new PET tracers such as HX-4, RGD-K5, and VM4-037, enabling safe clinical translation. He investigates quantitative Y-90 PET imaging for liver cancer radioembolization and applies textural analysis to predict treatment response. His preclinical studies explore Cerenkov imaging as a cost-effective method for evaluating radiotracer targeting.
The recent publications reflect a strong trend in translational medical physics, combining clinical PET/CT with preclinical models to advance oncologic imaging. His work emphasizes radiation safety, dosimetry accuracy, and the development of targeted imaging agents for hypoxia, angiogenesis, and apoptosis. The integration of quantitative imaging with therapeutic monitoring highlights a move toward personalized cancer care.
Dr. Doss has received several honors, including:
- Outstanding Leadership Award in the Field of Dose Response, International Dose-Response Society (2014)
- FCCC Ovarian SPORE Career Development Award (2003)
His research is supported by institutional and collaborative grants, particularly through multi-center initiatives like the QUEST study on Y-90 PET quantification. While no formal students are listed, his leadership in research projects suggests mentorship of junior scientists and physicists. He has not received external fellowships but has led significant methodological advancements in dosimetry and imaging.
Dr. Doss works within a multidisciplinary team at Fox Chase Cancer Center, utilizing state-of-the-art PET/CT scanners and software like OLINDA/EXM for dose estimation. His lab conducts human and animal studies, contributing to both clinical protocols and preclinical validation of imaging agents.
حوزههای پژوهشی
