Yuni Dewaraja

Yuni Dewaraja, PhD is the William Martel Research Professor in the Department of Radiology at the University of Michigan Medical School. She is affiliated with the Center for Positron Emission Tomography and has made significant contributions to the field of nuclear medicine physics and radiopharmaceutical therapy dosimetry.

Dr. Dewaraja earned her PhD in 1994 from the University of Michigan, following an MS from Kansas State University in 1990 and a BS from the University of Western Australia in 1986. Her academic journey has positioned her as a leading expert in quantitative imaging and radiation dosimetry.

Dr. Dewaraja's research focuses on estimating radiation absorbed dose in radionuclide therapy, quantitative SPECT imaging, image reconstruction techniques, and correction methods for scatter, attenuation and partial volume effects. She extensively employs Monte Carlo methods for image reconstruction and patient-specific absorbed dose estimation. Her work bridges physics, engineering, and clinical applications to improve the precision of targeted radionuclide therapies.

Her recent publications demonstrate a strong emphasis on Lutetium-177 and Yttrium-90 therapies, with research spanning dosimetry standardization, predictive modeling of treatment response, optimization of imaging protocols, and integration of multiple therapeutic modalities. She has been instrumental in international efforts to reduce variability in dosimetry calculations and establish best practices in the field.

• Can 177Lu-DOTATATE Kidney Absorbed Doses be Predicted from Pretherapy SSTR PET?
• Multicycle Dosimetric Behavior and Dose–Effect Relationships in [177Lu]Lu-DOTATATE Therapy
• Shorter SPECT scans using self-supervised coordinate learning techniques
• Sequential 90Y SIRT and SBRT using PET-based Absorbed Dose Maps
• 177Lu-PSMA-617 SPECT/CT Dosimetry and Radiobiological Models

Dr. Dewaraja has received recognition through numerous citations of her work, with over 3,000 total citations according to the Michigan Research Experts profile. Her research has been featured in leading journals including the Journal of Nuclear Medicine (93 publications), European Journal of Nuclear Medicine and Molecular Imaging (30 publications), and Medical Physics (12 publications).

As a dedicated educator and mentor, Dr. Dewaraja collaborates extensively with colleagues across multiple institutions on research projects focused on advancing precision in nuclear medicine therapy. Her work has significant implications for improving the safety and efficacy of targeted radionuclide treatments for cancer patients.