Mohammed Aleskandarany

Mohammed Aleskandarany is a Senior Lecturer in Biomedical Science (Histopathology) at the College of Science and Engineering. His research focuses on molecular mechanisms underlying breast cancer progression, with an emphasis on identifying prognostic biomarkers and understanding tumor heterogeneity. He has contributed to studies on glutamine metabolism in luminal breast cancer, centrosome amplification in hypoxic cancer cells, and the role of HSP90α in invasive breast cancer prognosis.

His work integrates clinical pathology with molecular biology, particularly exploring how genetic and protein markers influence cancer outcomes. Recent studies highlight his interest in predictive modeling using machine learning (e.g., GraphX-Net) and multi-institutional cohort analyses for triple-negative breast cancer.

Dr. Aleskandarany’s publications span over a decade, emphasizing translational research in breast cancer subtypes. Notable findings include the identification of SLC1A5 as a key metabolic regulator and the prognostic role of cell cycle traverse rates. His research also addresses tumor microenvironment dynamics, such as hypoxia-driven oncogenic pathways and immune cell interactions.