معرفی
Mireille Khacho is an Assistant Professor in the Department of Biochemistry, Microbiology and Immunology at the Faculty of Medicine, University of Ottawa. Her research focuses on understanding how mitochondrial dynamics and metabolism regulate stem cell behavior in health and disease, particularly in contexts such as cancer, aging, neurodegeneration, and muscular dystrophy. She employs cutting-edge techniques including live-cell imaging, proteomics, and genetic models to explore these mechanisms.
Key research interests include:
- Mitochondrial signaling pathways in stem cell fate decisions
- Role of mitochondria in cancer metastasis and tumor biology
- Mitochondrial dysfunction in neurodegenerative diseases and aging
- Metabolic adaptations in muscle stem cells and their implications for muscle regeneration
Her recent work highlights mitochondrial dynamics' role in regulating stem cell quiescence, differentiation, and survival under stress conditions. This research has implications for developing therapeutic strategies targeting mitochondrial pathways in diseases like muscular dystrophy, cancer, and neurodegenerative disorders.
