معرفی
Dr. Keir Menzies is an Associate Professor at the Interdisciplinary School of Health Sciences, University of Ottawa, with cross-appointments to the Department of Biochemistry, Microbiology and Immunology in the Faculty of Medicine. His research focuses on NAD+ signaling, mitochondrial function, and stem cell health in the context of aging, neuromuscular diseases, and placental dysfunction.
Research Interests: Dr. Menzies explores metabolic signaling pathways that regulate mitochondrial function in muscle and other organs. His work bridges systems biology, animal phenotyping, and molecular biology to develop translational strategies for aging and neuromuscular disorders. Notably, he investigates NAD+ homeostasis in muscle health, stem cell longevity, and pregnancy complications like preeclampsia.
Article Trends: Dr. Menzies’ recent publications emphasize NAD+ metabolism in placental dysfunction, mitochondrial biology in aging, and epigenetic modulation of muscle atrophy. His work spans biochemistry, obstetrics, and systems physiology, with a focus on ferroptosis, PARP pathways, and HDAC inhibition.
Scientific Awards:
- NSERC CREATE Program Funding
- CIHR Grants
- OIRM Grants
- MDC Support
- AFM-Téléthon Funding
Grants and Collaborations: Dr. Menzies’ research is funded by diverse agencies, including NSERC, CIHR, and AFM-Téléthon. He leads the MATRIX program, a collaborative metabolomics training initiative under NSERC.
Labs and Teams: His lab combines systems biology, animal phenotyping, and molecular techniques to study energy metabolism. Affiliated with the Ottawa Institute for Systems Biology, uOBMRI, CNMD, and OIRM, his team investigates metabolic networks in muscular dystrophy and pregnancy complications.
