معرفی
Dr. Vahab Soleimani is an Associate Professor in the Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Canada, and an Affiliate Investigator at the Ottawa Hospital Research Institute (OHRI). He leads the Soleimani Laboratory, which investigates molecular mechanisms governing muscle stem-cell function and skeletal-muscle regeneration.
Education
- BSc (Biology, Biotechnology) – University of Ottawa, 1998
- PhD – University of Ottawa, 2005
Research Focus
The laboratory studies satellite cells—quiescent muscle stem cells essential for lifelong muscle repair. Work centers on genetic and epigenetic circuits that maintain their regenerative potential, interactions with the stem-cell niche, and strategies to rejuvenate aged or diseased muscle stem cells. Key goals include translating findings into therapies for muscular dystrophies, cachexia, and age-related muscle wasting.
Publication Trends
Recent publications (2020-2025) demonstrate an emphasis on single-cell and single-myofiber genomics (ATAC-seq, RNA-seq), ubiquitin-ligase control of quiescence, transcriptional reprogramming by the niche, and pre-clinical models of aging and transplantation. Studies span basic stem-cell biology, methodological innovations, and translational applications in aging and cancer.
Scientific Awards & Honors
- No specific awards listed in the provided text.
Funding & Grants
While explicit grant numbers are not provided, the continuity of laboratory operations at two major Canadian universities (McGill 2014-2023; Ottawa 2023-present) and publication output in high-impact journals indicate sustained national or international peer-reviewed funding.
Laboratory & Team
The Soleimani Laboratory is housed in Roger Guindon Hall, Rooms 4113 (office) and 4253 (wet lab), University of Ottawa. The group employs advanced molecular, genomic, and imaging approaches to dissect muscle-stem-cell biology in health, aging, and disease.
