Miller Huang

Miller Huang is an Assistant Professor of Pediatrics at the University of Southern California (USC), affiliated with Children’s Hospital Los Angeles. His research focuses on developing human pluripotent stem cell-based models to study pediatric cancers such as medulloblastoma and neuroblastoma. He investigates genetic drivers, therapeutic vulnerabilities, and signaling pathways involved in tumor initiation and progression.

Education:

• Bachelor’s degree in Bioengineering from UC Berkeley
• PhD in Molecular Pathology from UC San Diego

Research interests include modeling genetic predispositions in stem cells, identifying therapeutic targets, and understanding oncogenic pathways such as MYCN overexpression and EGFR-mediated metastasis. His work bridges basic science with translational applications, leveraging precision genome editing and stem cell engineering.

Publications highlight advancements in stem cell-derived tumor models, molecular mechanisms of pediatric cancers, and signaling pathways like ALK/WNT and SHH. His studies often emphasize cooperative oncogenic interactions and vulnerabilities in cancer biology.

Notable contributions include developing models for medulloblastoma and neuroblastoma, exploring N-Myc translational control, and dissecting EGFR/integrin signaling in metastasis. His research aims to translate these findings into clinical therapies for pediatric cancers.