معرفی
Dr. Ahmet Ucar is an Honorary Research Fellow in the Division of Cancer Sciences at the University of Manchester, contributing to research aligned with the Manchester Cancer Research Centre. His work focuses on breast cancer biology, cancer stem cells, integrin signaling, and microRNA regulation in cancer progression and therapy resistance.
Research interests include understanding mechanisms driving breast tumor initiation, metastasis, and chemoresistance, with a focus on non-cell-autonomous effects of HER2 overexpression and RAC1B signaling in cancer stem cells. He also investigates circadian rhythm regulation via microRNAs and the role of β3-integrins in linking breast development to oncogenesis.
Recent publications highlight studies on oxidative stress-induced tumorigenesis, ERK5-mediated metastasis in triple-negative breast cancer, and the therapeutic potential of targeting P-Rex1/Rac1 pathways in cancer stem cells. Collaborative work spans international teams, with studies published in Oncogene, Breast Cancer Research, and PLoS ONE.
Dr. Ucar’s research supports the UN Sustainable Development Goals through advancements in cancer diagnosis, treatment, and understanding of disease mechanisms.
