Mildred Scheel

Mildred Scheel is a researcher at the University of Würzburg's Medical School, associated with the Mildred Scheel Cancer Research Center (MSNZ). She leads a junior research group investigating the intersection of nuclear RNA metabolism, paraspeckle biology, and genome maintenance in cancer contexts.

• PhD in Biology (2013, Ludwig Maximilian University of Munich)
• Postdoctoral research (University of Oxford, 2013-2019)

Her work focuses on RNA-binding proteins, long non-coding RNAs like NEAT1, and their roles in DNA damage response and tumorigenesis. Recent publications highlight Dicer dynamics in DNA repair, c-Abl kinase interactions with transcription machinery, and paraspeckle deregulation in cancer.

Research interests include:

• RNA-dependent pathways for genomic stability
• Mechanisms linking paraspeckles to tumor suppression
• Role of nuclear bodies in DNA repair

Scientific contributions include:

• 2017 discovery of nuclear phosphorylated Dicer in DNA damage
• 2018 work on Dicer re-localization following DNA damage
• 2019 study connecting c-Abl kinase to RNA polymerase II transcription
• 2021 review on nucleolar lncRNA functions

She received a fellowship from the José Carreras Leukemia Foundation during her PhD training (2009-2011). Her group combines molecular cell biology, biochemistry, transcriptomics, and tumor models to unravel paraspeckle dynamics in genome stability.