Mihajlo Novakovic

Dr. Mihajlo Novakovic is a researcher at the Biomolecular NMR Group (Institute of Biochemistry, ETH Zurich). His work focuses on advancing NMR spectroscopy techniques for structural and dynamical studies of labile biological systems, particularly RNA-protein interactions in SARS-CoV-2 and glycan structures.

• Primary Affiliation: ETH Zurich, Institute of Biochemistry
• Specialization: Sensitivity-enhanced NMR experiments, biomolecular condensates, and RNA structural biology.

Research Highlights:

• Developed LLPS REDIFINE for characterizing multicomponent condensates without labeling.
• Optimized Hadamard magnetization transfer for studying labile protons in SARS-CoV-2 RNA.
• Engineered cross-polarization schemes to improve heteronuclear NMR transfers involving labile protons.
• Explored glycan flexibility and signal resolution challenges through integrative NMR approaches.

Publication Trends: His recent work emphasizes RNA structure, protein-RNA interactions, glycan dynamics, and advanced NMR methodologies, particularly for SARS-CoV-2-related systems.